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Adding the Antibiotic Clofazimine to Chemotherapy for Triple Negative Breast Cancer in Nigeria

Adding the Antibiotic Clofazimine to Chemotherapy for Triple Negative Breast Cancer in Nigeria Principal Investigator: Dr. Atara Ntekim Disease: Breast cancer Research Description: Breast cancer causes high cancer related death globally. A type called triple negative...



Combining the Cholesterol-Lowering Drug Simvastatin with N-Acetylcysteine for Chronic Pancreatitis in India

Combining the Cholesterol-Lowering Drug Simvastatin with N-Acetylcysteine for Chronic Pancreatitis in India Principal Investigator: Dr. Rajiv Mehta Disease: Chronic pancreatitis Research Description: Chronic pancreatitis (CP) is a clinical challenge in India, and the...

Repurposing a Widely Available Antiseptic in Pediatric Chronic Ear Infections in Nigeria

Repurposing a Widely Available Antiseptic in Pediatric Chronic Ear Infections in Nigeria Principal Investigator: Dr. Mercy Jatto​​ Disease: Chronic suppurative otitis media Research Description: Chronic suppurative otitis media (CSOM) is inflammation of the lining of...


Enhancing Treatment Response in Recurrent/Metastatic Osteosarcoma with Hydroxychloroquine

Enhancing Treatment Response in Recurrent/Metastatic Osteosarcoma with Hydroxychloroquine Principal Investigator: Dr. Nancy Gordon​ Disease: Osteosarcoma Research Description: Osteosarcoma (OS) is an orphan disease affecting approximately 400 children and adolescents...

Repurposing the Blood Pressure Drug Minoxidil for the Treatment of Recurrent Chemo-Resistant Ovarian and Other Gynecological Cancers

Repurposing the Blood Pressure Drug Minoxidil for the Treatment of Recurrent Chemo-Resistant Ovarian and Other Gynecological Cancers Principal Investigator: Dr. Margaret Liotta Disease: Ovarian cancer Research Description: Epithelial ovarian cancer is the most lethal...



Repurposing the Antiviral Drug Valganciclovir to Treat Cytomegalovirus-Induced Hearing Loss

Repurposing the Antiviral Drug Valganciclovir to Treat Cytomegalovirus-Induced Hearing Loss Principal Investigator: Dr. Joseph Rower​​ Disease: Hearing loss Research Description: Almost 400 children die each year from congenital cytomegalovirus (cCMV) infections, and...


Improving Outcomes for the Rare Liver Disease Biliary Atresia with a Cancer Drug in Vietnam

Improving Outcomes for the Rare Liver Disease Biliary Atresia with a Cancer Drug in Vietnam Principal Investigator: Dr. Anh-Hoa Pham Nguyen​ Disease: Biliary atresia Research Description: Biliary atresia (BA) is a rare congenital liver disease that causes bile duct...



Preventing Relapse After Bone Marrow Transplant in Pediatric Acute Lymphoblastic Leukemia with a Personalized Treatment

Preventing Relapse After Bone Marrow Transplant in Pediatric Acute Lymphoblastic Leukemia with a Personalized Treatment Principal Investigator: Dr. Alix Seif Disease: Acute Lymphoblastic Leukemia Research Description: Pediatric acute lymphoblastic leukemia (ALL)...


Treating a Group of Rare Blood Cancers, Myeloproliferative Neoplasms, with N-Acetylcysteine

Treating a Group of Rare Blood Cancers, Myeloproliferative Neoplasms, with N-Acetylcysteine Principal Investigator: Dr. Angela Fleischman​ Disease: Myeloproliferative neoplasms: Polycythemia vera, essential thrombocythemia and myelofibrosis Research Description:...