Diabetes | Massachusetts General Hospital | Dr. Faustman | Repurposing a Vaccine for Type I Diabetes | Vaccine | Adult | In Process |
Diabetic Ophthalmology | Northwestern University | Dr. Basti | Treating Cataracts in Diabetic Patients Using a Surgical Device | Device | Adult | In Process |
Ear Nose Throat | House Institute Foundation | Dr. Derebery | Reducing vertigo and hearing loss in Meniere’s disease by repurposing a common allergy drug | Drug | Adult | In Process |
Ear Nose Throat | ibs.GRANADA | Dr. Gallego-Martinez | Searching for Pharmacogenetic Targets in Meniere’s Disease Patients | Drug | Pre-Clinical | Started 2022 |
Ear Nose Throat | Medical University of South Carolina | Dr. Rizk | Assessing the efficacy of an antidepressant for improving vertigo attacks in Meniere’s disease | Drug | Adult | In Process |
Ear Nose Throat | Hospital of the Ludwig-Maximilians University, Munich | Dr. Strupp | Combining a vertigo drug with a Parkinson’s disease drug to treat the inner ear disorder, Meniere’s disease | Drug | Adult | In Process |
Ear Nose Throat | Dent Neurologic Institute | Dr. Zhang | Combining an anti-epileptic drug with an anti-anxiety drug to treat the inner ear disorder Meniere’s disease | Drug | Adult | In Process |
Ear Nose Throat | Hospital of the Ludwig-Maximilians University, Munich | Dr. Zwergal | Identifying a Potential Biomarker and Repurposed Migraine Treatment in Meniere’s disease | Drug | Adult | Started 2022 |
Ear Nose Throat/Infectious Disease | University College Hospital Ibadan | Dr. Jatto
- Researcher Spotlight available here | Repurposing a Widely Available Antiseptic in Pediatric Chronic Ear Infections in Nigeria | Drug | Pediatric | Started 2022 |
Ear Nose Throat/Infectious Disease/Rare | University of Utah | Dr. Rower | Repurposing the Antiviral Drug Valganciclovir to Treat Cytomegalovirus-Induced Hearing Loss | Drug | Pediatric | In Process |
Immune Disorder/Rare | Cincinnati Children's Hospital Medical Center | Dr. Abonia
- Researcher Spotlight available here | Repurposing a Rare Disease Treatment for the Immune Disorder Eosinophilic Esophagitis | Drug | Adult | Started 2022 |
Immune Disorder/Rare | St. Jude Children’s Research Hospital | Dr. Nichols | Repurposing a Blood Cancer Drug to Treat an Immune Disorder (HLH) in Children* | Drug | Pediatric | In Process |
Infectious Disease | George Washington University, Universidad El Bosque | Dr. Chang | Repurposing a Flu Treatment for Severe Dengue Patients in Colombia | Drug | Pediatric | In Process |
Infectious Disease | University of Chicago | Dr. Meltzer | Can Vitamin D Reduce the Burden of COVID-19 in Chicago? | Nutraceutical | Adult | In Process |
Inflammatory Disease | SIDS Hospital and Research Centre | Dr. Mehta | Combining the Cholesterol-Lowering Drug Simvastatin with N-Acetylcysteine for Chronic Pancreatitis in India | Drug | Adult | Started 2022 |
Liver Disease/Rare | Vietnam National Children’s Hospital/Big Leap Research | Dr. Nguyen | Improving Outcomes for the Rare Liver Disease Biliary Atresia with a Cancer Drug in Vietnam | Drug | Pediatric | In Process |
Neuro | University of California, Los Angeles | Dr. Ackerman | Testing a Repurposed Device to Improve the Treatment of Chronic Pelvic Pain in Women | Device | Adult | Started 2022 |
Neuro | University of New Mexico | Dr. Lewine | Repurposing N-Acetylcysteine to Reduce Oxidative Stress, an Important Factor in Traumatic Brain Injury | Drug | Adult | Started 2022 |
Neuro | Rush University Medical Center | Dr. Voigt-Zuwala | Enhancing Posttraumatic Stress Disorder Treatment for Veterans via Prebiotic Supplementation | Nutraceutical | Adult | In Process |
Neuro | Edward Hines Jr VA Hospital and CARES | Dr. Bender Pape | Using an Approved Depression Treatment to Restore Cognitive Function in Veterans with Mild TBI and PTSD | Device | Adult | Started 2022 |
Neuro | Advocate Aurora Health | Dr. Burek | Testing a Low-Dose of the Hypertension Drug Clonidine for PTSD in Veterans | Drug | Adult | Started 2022 |
Neuro/Infectious Disease | Emory University School of Medicine | Dr. McKenzie-Brown - Researcher Spotlight available here | Addressing Chronic Pain in HIV Patients with an Approved Addiction Treatment | Drug | Adult | Started 2022 |
Neuro/Rare | McGovern Medical School at The University of Texas Health Science Center at Houston | Dr. Furr-Stimming | Treating Irritability in Huntington’s Disease with a Repurposed Neurological Drug | Drug | Adult | In Process |
Oncology/Rare | University of California, Irvine | Dr. Fleischman | Treating a Group of Rare Blood Cancers, Myeloproliferative Neoplasms, with N-Acetylcysteine* | Drug | Adult | In Process |
Oncology/Rare | The University of Texas MD Anderson Cancer Center | Dr. Gordon
- Researcher Spotlight available here | Enhancing Treatment Response in Recurrent/Metastatic Osteosarcoma with Hydroxychloroquine* | Drug | Pediatric | In Process |
Oncology/Rare | Loyola University Medical Center | Dr. Liotta | Repurposing the Blood Pressure Drug Minoxidil for the Treatment of Recurrent Chemo-Resistant Ovarian Cancer | Drug | Adult | In Process |
Oncology/Rare | University Hospital College Ibadan | Dr. Ntekim
- Researcher Spotlight available here | Adding the Antibiotic Clofazimine to Chemotherapy for Triple Negative Breast Cancer in Nigeria | Drug | Adult | Started 2022 |
Oncology/Rare | University of Illinois Chicago | Dr. Sims | Repurposing a Diagnostic Device to Address Health Disparities in Esophageal Cancer Screening and Outcomes | Device / Diagostic | Adult | Started 2022 |
Oncology/Rare | Children’s Hospital of Philadelphia | Dr. Seif | Preventing Relapse After Bone Marrow Transplant in Pediatric Acute Lymphoblastic Leukemia (ALL) with a Personalized Treatment | Drug | Pediatric | In Process |
Oncology/Rare | University of Michigan | Dr. Swiecicki | Repurposing Old Drugs as New Therapies for Metastatic Thyroid Cancer* | Drug | Adult | In Process |
Oncology/Rare | Massachusetts General Hospital/Harvard Medical School, VUmc Cancer Center Amsterdam | Drs. Tannous, Arrillaga-Romany, Kouwenhoven | A Novel Combination of Generic Chemotherapy Drugs to Treat Brain Cancer | Drug | Adult | In Process |
Ophthalmic/Rare | University of California, Davis | Dr. Park | Repurposing Bone Marrow Stem Cell Therapy for Vision Loss Caused by Retinitis Pigmentosa | Other | Adult | In Process |
Ophthalmic/Rare | University of Michigan | Dr. Zacks | Testing a Generic Malarial Drug in a Rare Ophthalmic Condition, Retinitis Pigmentosa | Drug | Adult | In Process |
Other | KEMRI-Wellcome Trust Research Programme | Dr. Hamaluba
- Researcher Spotlight available here | Testing the Safety of a Metal Poisoning Drug to Treat Snakebite in Kenya | Drug | Adult | In Process |
Rare/Vascular | Stanford University | Dr. Teng | Treating Vascular Malformations Using the Cancer Drug Trametinib* | Drug | Pediatric | In Process |