Cures Within Reach’s mission is to leverage the speed, safety and cost-effectiveness of repurposing, testing already approved therapies for unsolved diseases: driving more treatments to more patients more quickly.
Cures Within Reach is the philanthropic leader in drug, device and nutraceutical repurposing research, which has the potential to transform the lives of patients with unsolved diseases by delivering treatments that can be used in the near-term. Our focus: we find and fund proof-of-concept clinical trials that, once successful, de-risk and catalyze follow-on funding, building the clinical evidence required for regulatory approval or to support off-label use by patients everywhere.
Our AI Validation RFP is Now Accepting Submissions
The first RFP to fund clinical trials that will validate AI-driven drug-disease matches is accepting LOI submissions until August 25, 2025. These investigator-initiated, proof of concept, Phase I or Phase IIA clinical repurposing trials will include AI-generated data as part of the preclinical support for the trial. Eligibility: any unsolved disease is eligible, although there is a preference for rare diseases; both on- and off-patent drugs and biologics are eligible, although there is a preference for off-patent; and data from any AI model is eligible, although there is a preference for openly accessible models and for models developed by nonprofits/government. Visit our Funding Opportunity RFP page for details!
Our 2024 Annual Report is available here.
Read about our newest success stories in blood cancer and snakebite, and our other exciting achievements in 2024:
- $29 million in follow-on funding raised for our funded research(ers)
- 13 clinical trials started
Read our recent news releases here, including in December 2024 about our LMIC efforts and for AI Validation trials.
Learn about our 2025 initiatives:
in Pediatrics
for Veterans/Military
and in AI Validation
Upcoming / Recent Events
Virtual Event: Best Practices in Engaging Community Health Organizations in Clinical Trials
October 28, 2024 at 5:30pm ET: a dialogue on the value of community health organizations to support screening and enrollment opportunities for active clinical trials with sites nearby, especially for clinical researchers, clinical research teams and related institution efforts
Diseases Researched
Repurposing Trials Funded
Institutions Funded
Success Stories
Startups with Our Investments
Companies Commercializing Our Research
Millions of Dollars in Clinical Trial Funding
