Cures Within Reach’s mission is to leverage the speed, safety and cost-effectiveness of repurposing, testing already approved therapies for unsolved diseases: driving more treatments to more patients more quickly.

Cures Within Reach is the philanthropic leader in drug, device and nutraceutical repurposing research, which has the potential to transform the lives of patients with unsolved diseases by delivering treatments that can be used in the near-term. Our focus: we find and fund proof-of-concept clinical trials that, once successful, de-risk and catalyze follow-on funding, building the clinical evidence required for regulatory approval or to support off-label use by patients everywhere.

Check out our 2025 Annual Report available here!

Read about our 20th anniversary celebration and our record-breaking 2025:

  • $17 million raised in catalytic, follow-on funding for our funded research
  • A record 16 clinical trials started
  • A record 12 clinical trials completed
  • A record 16 clinical trials selected, already underway or starting soon
  • A record number of submissions received

 

Learn about some of our 2026 initiatives: 

in Pediatrics

for Veterans/Military

and in AI Validation

Our AI Validation RFP 

The first RFP to fund clinical trials that will validate AI-driven drug-disease matches accepted LOI submissions until August 25, 2025. These investigator-initiated, proof of concept, Phase I or Phase IIA clinical repurposing trials will include AI-generated data as part of the preclinical support for the trial. Eligibility: any unsolved disease is eligible, although there is a preference for rare diseases; both on- and off-patent drugs and biologics are eligible, although there is a preference for off-patent; and data from any AI model is eligible, although there is a preference for openly accessible models and for models developed by nonprofits/government. Visit our Funding Opportunity RFP page for details!

Upcoming / Recent Events

Virtual Event: Engaging Social Services and Faith-Based Organizations in Clinical Trials
October 16, 2025 at 5pm ET: a dialogue on the value of social services and faith-based community organizations to support screening and enrollment opportunities for active clinical trials with sites nearby, especially for clinical researchers, clinical research teams and related institution efforts

clinical research for unsolved diseases

Diseases Researched

repurposing research grants funding

Repurposing Trials Funded

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Institutions Funded

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Success Stories

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Millions of Dollars in Clinical Trial Funding

repurposing-research-initiated -follow-on-funding supporting clinical research

Millions of Dollars in Follow-on Funding Leveraged