Autoimmune | Massachusetts General Hospital | Dr. Faustman | Repurposing a Vaccine for Type I Diabetes | Vaccine | Adult | Completed 2024 |
Diabetic Ophthalmology | Northwestern University | Dr. Basti | Treating Cataracts in Diabetic Patients Using a Surgical Device | Device | Adult | Completed 2023 |
Ear Nose Throat | Curtin University | Dr. Brown | Testing a Generic Diuretic to Improve Drug Delivery to the Inner Ear in Meniere’s Disease | Drug | Pre-Clinical | Completed 2021 |
Ear Nose Throat | Stanford Medicine | Drs. Grimes, Santa Maria | Modulating Inner Ear Fluid Regulation to Treat Meniere’s Disease | Drug | Pre-Clinical | Completed 2022 |
Ear Nose Throat | The Feinstein Institutes for Medical Research | Dr. Pathak | Investigating the Effects of Repurposed Diuretic, Steroid and Immunosuppressive Drugs in Meniere’s Disease | Drug | Pre-Clinical | Completed 2023 |
Ear Nose Throat | Medical University of South Carolina | Dr. Rizk
- Researcher Spotlight available here | Assessing the Efficacy of an Antidepressant for Improving Vertigo Attacks in Meniere’s Disease | Drug | Adult | Completed 2023 |
Ear Nose Throat | University Hospital of Munich | Dr. Strupp - Researcher Spotlight available here | Combining a Vertigo Drug with a Parkinson’s Disease Drug to Treat the Inner Ear Disorder, Meniere’s Disease | Drug | Adult | Completed 2023 |
Ear Nose Throat | Dent Neurologic Institute | Dr. Zhang | Combining an Anti-Epileptic Drug with an Anti-Anxiety Drug to Treat the Inner Ear Disorder Meniere’s Disease | Drug | Adult | Completed 2024 |
Ear Nose Throat | ibs.GRANADA | Dr. Gallego-Martinez | Searching for Pharmacogenetic Targets in Meniere’s Disease Patients | Diagnostic | Pre-Clinical | Completed 2024 |
Ear Nose Throat/Infectious Disease | University College Hospital Ibadan | Dr. Jatto
- Researcher Spotlight available here | Repurposing a Widely Available Antiseptic in Pediatric Chronic Ear Infections in Nigeria | Drug | Pediatric | Completed 2023 |
Ear Nose Throat/Infectious Disease/Rare | University of Utah | Dr. Rower - Researcher Spotlight available here | Repurposing the Antiviral Drug Valganciclovir to Treat Cytomegalovirus-Induced Hearing Loss | Drug | Pediatric | Completed 2024 |
GI | OpenBiome, University of Cape Town | Drs. Osman, Budree | The THRIVE Study: Repurposing Fecal Microbiota Transplantation for the Treatment of Pediatric Malnutrition in South Africa * | Other | Pediatric | Completed 2020 |
Infectious Disease | Northwestern University | Dr. Rado | Repurposing an Antidepressant to Prevent Hospitalization in COVID-19 | Drug | Adult | Completed 2021 |
Infectious Disease | Obafemi Awolowo University & Teaching Hospitals Complex | Prof. Adewole
- Researcher Spotlight available here | Treating Tuberculosis with the Lipid Lowering Drug Atorvastatin in Nigeria | Drug | Adult | Completed 2022 |
Infectious Disease/GI | Boston Children's Hospital | Dr. Kahn | Fecal Microbiota Transplantation Patient Registry for Pediatric C-diff | Other | Pediatric | Completed 2021 |
Liver Disease/Rare | Children's National Health System, University of Illinois at Chicago | Dr. Nadler, Dr. Holterman | Using a Cancer Drug to Treat a Rare Pediatric Liver Disease | Drug | Pediatric | Completed 2019 |
Metabolic Disorder/Rare | Children's Hospital of Philadelphia, The Hospital for Sick Children | Drs. Levine, Sochett
- Researcher Spotlight available here | Repurposing an Antibiotic to Treat a Defect in Vitamin D Metabolism | Drug | Pediatric | Completed 2020 |
Neuro | University of Pennsylvania Medicine | Dr. Oathes - Researcher Spotlight available here | Using Imaging Techniques to Guide Targeted Brain Stimulation in the Treatment of Depression and Post-Traumatic Stress Disorder | Device | Adult | Completed 2021 |
Neuro/Rare | McGovern Medical School at The University of Texas Health Science Center at Houston | Dr. Furr-Stimming - Researcher Spotlight available here | Treating Irritability in Huntington’s Disease with a Repurposed Neurological Drug | Drug | Adult | Completed 2023 |
Neuro | The Pennsylvania State University and the Milton S. Hershey Medical Center | Dr. Elfar
- Researcher Spotlight available here | Repurposing a Multiple Sclerosis Drug in Severe Limb Trauma* | Drug | Adult | Completed 2022 |
Neuro | Cincinnati Children's Hospital Medical Center | Dr. Wink | Repurposing a Generic Drug in Autism Spectrum Disorder | Drug | Pediatric | Completed 2019 |
Neuro | University of Toronto | Dr. Lanctôt - Researcher Spotlight available here | A New Opportunity to Treat Behavioral Problems in Alzheimer’s Patients | Drug | Adult | Completed 2019 |
Neuro | University of New Mexico | Dr. Lewine - Researcher Spotlight available here | Repurposing N-Acetylcysteine to Reduce Oxidative Stress, an Important Factor in Traumatic Brain Injury | Drug | Adult | Completed 2023 |
Neuro | Rush University Medical Center | Dr. Voigt-Zuwala - Researcher Spotlight available here | Enhancing PTSD Treatment for Veterans via Prebiotic Supplementation | Nutraceutical | Adult | Completed 2024 |
Neuro/Rare | Georgetown University | Dr. Anderson | Using a Cancer Drug in Huntington's Disease | Drug | Adult | Completed 2022 |
Oncology | University of Chicago | Drs. Chmura, Bestvina | Innovations in Combination Therapies for Non-Small Cell Lung Cancer | Drug | Adult | Completed 2020 |
Oncology/Rare | Johns Hopkins Medicine | Dr. Riggins | A Phase I Trial for Recurrent Pediatric Brain Cancers Using a Repurposed Generic Drug | Drug | Pediatric | Completed 2019 |
Oncology/Rare | University of Michigan | Dr. Swiecicki | Repurposing Old Drugs as New Therapies for Metastatic Thyroid Cancer* | Drug | Adult | Completed 2024 |
Oncology/Rare | University of Illinois Chicago | Dr. Sims - Researcher Spotlight available here | Repurposing a Diagnostic Device to Address Health Disparities in Esophageal Cancer Screening and Outcomes | Device / Diagostic | Adult | Completed 2025 |
Oncology/Rare | University of Pittsburgh | Dr. Ito | Investigating a Rare Disease Drug to Treat AML and MDS Patients with Post-Stem Cell Transplant Relapse | Drug | Adult | Completed 2025 |
Oncology/Rare/Neuro | Massachusetts General Hospital/Harvard Medical School, VUmc Cancer Center Amsterdam | Dr. Tannous | A Novel Combination of Generic Chemotherapy Drugs to Treat Brain Cancer | Drug | Adult | Completed 2023 |
Oncology/Rare | Ulm University | Dr. Halatsch | Combining Nine Repurposed Drugs with a Current Chemotherapy Treatment in Adult Brain Cancer | Drug | Adult | Completed 2020 |
Ophthalmic | University of Pennsylvania Medicine | Dr. Kim | Repurposing a Nutraceutical to Treat a Type of Age-Related Macular Degeneration | Nutraceutical | Adult | Completed 2019 |
Ophthalmic/Rare/Inherited Disorder | University of California, Davis | Dr. Park - Researcher Spotlight available here | Repurposing Bone Marrow Stem Cell Therapy for Vision Loss Caused by Retinitis Pigmentosa | Other | Adult | Completed 2023 |
Ophthalmic/Rare/Inherited Disorder | University of Michigan | Dr. Zacks | Testing a Generic Malarial Drug in a Rare Ophthalmic Condition, Retinitis Pigmentosa | Drug | Adult | Completed 2024 |
Other | KEMRI-Wellcome Trust Research Programme | Dr. Hamaluba
- Researcher Spotlight available here | Testing the Safety of a Metal Poisoning Drug to Treat Snakebite in Kenya | Drug | Adult | Completed 2023 |
Vascular | University of Illinois at Chicago | Drs. Havelka, Eton | Saving Limbs from Chronic Ischemia: Helping Nature Do Its Magic* | Drug/Device combo | Adult | Completed 2019 |