While Cures Within Reach is disease-agnostic and geography-agnostic, some of our funding partners have strategic interests in specific geographic regions.  Therefore, in addition to our disease-specific repurposing communities, we work to increase the repurposing research focused on improving the quality and length of life within the Developing World, specifically low and low-middle income countries (LMICs, as defined by the World Bank) through the speed and cost-effectiveness of medical repurposing.

Our events and research within the the Developing World / LMIC Repurposing Community all focus on connecting our many stakeholder groups together in our shared goal: driving more treatments to more patients more quickly through repurposing.

Read our news release from January 23, 2024 here, describing the 4 LMIC-based clinical trials recently selected!

Open Funding Opportunity for the Developing World / LMICs:

Impacting Blood Cancers through Clinical Repurposing Trials: clinical trials in LMICs are eligible! Accepting budgets of up to $75,000 from institutions worldwide for clinical repurposing trials targeting any blood cancer, with a preference for trials impacting multiple myeloma and/or myelodysplastic syndromes. LOI DEADLINE CLOSED; SUBMISSIONS UNDER REVIEW 

ReGRoW: Funding for Underresourced Researchers in Low and Lower-Middle Income Countries 2024: accepting budgets of up to $65,000 for clinical repurposing trials in any disease led by an underresourced researcher in any LMIC, as defined by the World Bank. FUNDING DECISIONS MADE

More information on our Funding Opportunities / RFPs page.

Our ongoing LMIC trials:

Four Trials from our 2023 RFP, ongoing now:

• Adding Beta-lactam Antibiotics to Shorten Buruli Ulcer Disease Therapy at Université d’Abomey-Calavi in Benin
• Testing a Generic Drug Combination to Treat AML in Tanzania at Muhimbili University Health and Allied Sciences in Tanzania 
• Using Sodium Bicarbonate to Reduce Maternal / Fetal Death from Acidosis During Obstructed Labor at Busitema University in Uganda 
• Adding Zinc to Reduce Sickle Cell Anemia-related Infections in Ugandan Children at Global Health Uganda in Uganda 

Three Trials from our 2022 RFP, ongoing now:

• Dr. Dinesh Mondal at International Centre for Diarrhoeal Disease Research, Bangladesh: Assessing Safety and Efficacy of Oral Ivermectin in Post Kala-Azar Dermal Leishmaniasis Treatment
• Dr. Stanley Zimba at University of Zambia School of Medicine: Testing an Antihypertensive Drug as an Add-On therapy for Drug-Resistant Epilepsy Patients in Zambia
• Dr. Fahafahantsoa Rapelanoro Rabenja at University of Antananarivo: Effect of methotrexate as a treatment for moderate to severe atopic dermatitis in Madagascar

Three Trials Funded in 2021, 2 ongoing now, 1 completed:

• For chronic pancreatitis patients in India
• For triple negative breast cancer in Nigeria
• In pediatric chronic ear infections in Nigeria (now completed)

Three Trials Based in LMICs Funded in 2020, 1 ongoing now, 2 completed:

COMPLETED: Dr. Hamaluba researching snakebites in Kenya	Dr. Nguyen researching a rare pediatric liver disease biliary atresia in Vietnam	COMPLETED: Dr. Adewole researching tuberculosis in Nigeria