While Cures Within Reach is disease-agnostic and geography-agnostic, some of our funding partners have strategic interests in specific geographic regions.  Therefore, in addition to our disease-specific repurposing communities, we work to increase the repurposing research focused on improving the quality and length of life within the Developing World, specifically low and low-middle income countries (LMICs, as defined by the World Bank) through the speed and cost-effectiveness of medical repurposing.

Our events and research within the the Developing World / LMIC Repurposing Community all focus on connecting our many stakeholder groups together in our shared goal: driving more treatments to more patients more quickly through repurposing.

Open Funding Opportunity for the Developing World / LMICs:

ReGRoW: Funding for Underresourced Researchers in Low and Lower-Middle Income Countries 2025: accepting budgets of up to $65,000 for clinical repurposing trials in any disease led by an underresourced researcher in any LMIC, as defined by the World Bank. SUBMISSIONS DUE MARCH 28, 2025.

More information on our Funding Opportunities / RFPs page.

Read our news release from December 9, 2024 here, describing the 6 LMIC-based clinical trials selected in 2024!

Read our news release from January 23, 2024 here, describing the 4 LMIC-based clinical trials selected in 2023!

Our ongoing LMIC trials:

Six Trials from our 2024 RFP selected:

• Preventing Prematurity with Xylitol in Malawi at Baylor Foundation Malawi
• Assessing a Combination Therapy for Helminthiasis in Bangladeshi Children at International Centre for Diarrhoeal Disease Research, Bangladesh
• Repurposing Lactoferrin and Lysozyme to Address Environmental Enteric Dysfunction in Kenya at KEMRI – Kenya Medical Research Institute
• Treating High-grade Cervical Intraepithelial Neoplasia with a Skin Cancer Drug in Nigeria at University of Lagos
• The Effect of Metformin on Weight Loss in Non-Diabetic, Obese Nigerians at University of Nigeria Teaching Hospital
• Comparing Two Drugs to Treat P. Malariae in Mali at University of Science, Technology and Engineering of Bamako

Four Trials from our 2023 RFP, ongoing now:

• Adding Beta-lactam Antibiotics to Shorten Buruli Ulcer Disease Therapy at Université d’Abomey-Calavi in Benin
• Testing a Generic Drug Combination to Treat AML in Tanzania at Muhimbili University Health and Allied Sciences in Tanzania 
• Using Sodium Bicarbonate to Reduce Maternal / Fetal Death from Acidosis During Obstructed Labor at Busitema University in Uganda 
• Adding Zinc to Reduce Sickle Cell Anemia-related Infections in Ugandan Children at Global Health Uganda in Uganda 

Three Trials from our 2022 RFP, ongoing now:

• Dr. Dinesh Mondal at International Centre for Diarrhoeal Disease Research, Bangladesh: Assessing Safety and Efficacy of Oral Ivermectin in Post Kala-Azar Dermal Leishmaniasis Treatment
• Dr. Stanley Zimba at University of Zambia School of Medicine: Testing an Antihypertensive Drug as an Add-On therapy for Drug-Resistant Epilepsy Patients in Zambia
• Dr. Fahafahantsoa Rapelanoro Rabenja at University of Antananarivo: Effect of methotrexate as a treatment for moderate to severe atopic dermatitis in Madagascar

Three Trials Funded in 2021, 2 ongoing now, 1 completed:

• For chronic pancreatitis patients in India
• For triple negative breast cancer in Nigeria
• In pediatric chronic ear infections in Nigeria (now completed)

Three Trials Based in LMICs Funded in 2020, 1 ongoing now, 2 completed:

COMPLETED: Dr. Hamaluba researching snakebites in Kenya	Dr. Nguyen researching a rare pediatric liver disease biliary atresia in Vietnam	COMPLETED: Dr. Adewole researching tuberculosis in Nigeria