Non-invasive Monitoring to Detect Food Allergic Reactions

​Principal Investigator: Dr. Christina Ciaccio

Disease: Food Allergy

Research Description:Food allergy is a common chronic disease that affects 8% of children in the US alone. There is no cure, and the FDA-approved treatment options don’t work for many patients. Furthermore, patients have no way of truly knowing if the approved treatments will be effective for them or not until they have a reaction to a food allergen. There is a need for diagnostic tests that evaluate if the approved treatment will work for each patient. This single center clinical trial is investigating non-invasive testing using a Doppler flow monitor to determine reactivity to food allergens and efficacy of treatments in patients already undergoing oral food challenge tests. If successful, data from this trial will be the basis for developing objective efficacy measure via diagnostics and a novel biomarker for food allergies, allowing patients to know if they are protected from potential allergic reactions.

Funding Partners: Searle Funds at The Chicago Community Trust, Walder Foundation and others

Initial CWR Funding Role: Supplemental