54aacd72cefc4

Chani Traube HeadshotPrincipal Investigator: Dr. Chani Traube

Disease: Pediatric delirium

Research Description: Delirium is disturbed consciousness, cognition and/or acute change in mental status and inattention. Delirium is recognized as a significant complication of critical illness, associated with increased mortality in adults. A growing body of pediatric literature suggests that delirium is a serious and under-recognized problem in critically ill children, yet little research has focused on treatment. Quetiapine, an FDA approved atypical antipsychotic, may be repurposed as an effective off-label treatment option for pediatric delirium. The proposed clinical research trial will test the drug in children diagnosed with delirium in the pediatric intensive care unit.

CWR funding role: Primary funder

Start date: October 1, 2015

Most recent report: Patient recruitment and data collection for this clinical trial are currently underway.

Anticipated next steps:

→ Data published in a scientific journal and/or presented at a scientific conference 

→ Data are supporting off-label clinical use

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