SarahKeim picPrincipal Investigator: Dr. Sarah Keim

Disease: Prematurity

Research Description: In the U.S., 1 in 8 babies is born prematurely. Children who are born preterm have an increased risk of cognitive deficits and learning disabilities compared with children who are born at term. Several trials have found that dietary supplementation with a fatty acid during infancy moderately benefits cognitive development of preterm children. Studies have not examined whether supplementation during the second year of life is beneficial, which is important since brain development remains very active at this time. Dr. Keim will test whether or not preterm children benefit from supplementation after age 12 months, to inform treatment and dietary recommendations for these children.

CWR funding role: Primary funder

Start date: March 1, 2015

Most recent report: Enrollment for this clinical trial continues, with 60 new participants recruited since July 2015. Data collection is also ongoing, with a survey response rate of 83%. Survey data collected include cognition measures, physical characteristics and diet. Two recent enhancements were added to increase the survey response rate: an initial phone call to introduce the survey before it was sent to participants and an entry into a quarterly drawing for completing the survey.

Anticipated next steps:

→ Data published in a scientific journal and/or presented at a scientific conference 

→ Data leveraged into larger philanthropic or government funding for this treatment

→ Data are supporting off-label clinical use

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